Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain.

The local translation of β-actin is one mechanism proposed to regulate spatially-restricted actin polymerization crucial for nearly all aspects of neuronal development and function. However, the physiological significance of localized β-actin translation in neurons has not yet been demonstrated in v...

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Bibliographic Details
Main Authors: Thomas R Cheever, Bin Li, James M Ervasti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3293915?pdf=render