The enhancement apoptosis of osteosarcoma mesenchymal stem cells co-cultivation with peripheral blood mononuclear cells sensitized by secretome and granulocyte macrophage colony-stimulating factor

The enhancement apoptosis of osteosarcoma mesenchymal stem cells co-cultivation with peripheral blood mononuclear cells sensitized by secretome and granulocyte macrophage colony-stimulating factor

The advanced, metastasis, and reccurent of osteosarcoma (OS) patients have a poor prognosis postaggresive surgery and chemotherapy. Peripheral blood mononuclear cells (PBMCs) as cell-based immunotherapy may successful in the OS treatment. To investigate the enhancement apoptosis of OS-mesenchymal st...

Full description

Bibliographic Details
Main Authors:	Ferdiansyah Mahyudin, Hizbillah Yazid, Mouli Edward, Mohammad Hardian Basuki, Yunus Abdul Bari, Fedik Abdul Rantam
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2020-01-01
Series:	Journal of Advanced Pharmaceutical Technology & Research
Subjects:	granulocyte macrophage colony stimulating factor mesenchymal stem cells osteosarcoma peripheral blood mononuclear cells secretome
Online Access:	http://www.japtr.org/article.asp?issn=2231-4040;year=2020;volume=11;issue=4;spage=213;epage=219;aulast=Mahyudin

Similar Items

The Escalation of Osteosarcoma Stem Cells Apoptosis After the Co-Cultivation of Peripheral Blood Mononuclear Cells Sensitized with Mesenchymal Stem Cells Secretome and Colony Stimulating Factor-2 in vitro
by: Mahyudin F, et al.
Published: (2021-07-01)

Prospect of stem cells conditioned medium (secretome) in ligament and tendon healing: A systematic review
by: Sholahuddin Rhatomy, et al.
Published: (2020-08-01)

Safety and clinical efficacy of the secretome of stressed peripheral blood mononuclear cells in patients with diabetic foot ulcer—study protocol of the randomized, placebo-controlled, double-blind, multicenter, international phase II clinical trial MARSYAS II
by: Alfred Gugerell, et al.
Published: (2021-01-01)

Aislamiento de células mononucleares de sangre periférica para trasplante de células madre: Método simplificado Isolation of mononuclear cells of peripheral blood for stem cell transplant: Simplified method
by: Lázaro Cortina Rosales, et al.
Published: (2008-12-01)

Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products
by: Maria Laggner, et al.
Published: (2020-01-01)

Mesenchymal Stem Cell Secretome as an Emerging Cell-Free Alternative for Improving Wound Repair
by: Parinaz Ahangar, et al.
Published: (2020-09-01)

Freeze-Dried Mesenchymal Stem Cell-Secretome Pharmaceuticalization: Optimization of Formulation and Manufacturing Process Robustness
by: Michela Mocchi, et al.
Published: (2021-07-01)

TGF-β in the Secretome of Irradiated Peripheral Blood Mononuclear Cells Supports In Vitro Osteoclastogenesis
by: Layla Panahipour, et al.
Published: (2020-11-01)

Topical Delivery of Mesenchymal Stem Cells “Secretomes” in Wound Repair
by: Indah Julianto, et al.
Published: (2016-11-01)

A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions
by: Serife Ayaz-Guner, et al.
Published: (2020-07-01)

Insights into the Effects of Mesenchymal Stem Cell-Derived Secretome in Parkinson’s Disease
by: Michele d’Angelo, et al.
Published: (2020-07-01)

Editorial: Tissue Repair and Regenerative Mechanisms by Stem/Progenitor Cells and Their Secretome
by: Roberto Gramignoli, et al.
Published: (2019-01-01)

Sex-dependent differences in the secretome of human endothelial cells
by: Maria Grazia Cattaneo, et al.
Published: (2021-01-01)

The secretome of skeletal muscle cells: A systematic review
by: Antoine Florin, et al.
Published: (2020-03-01)

Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome
by: Patrizio Mancuso, et al.
Published: (2019-01-01)

Metformin pre-conditioning enhances the angiogenic ability of the secretome of dental pulp stem cells
by: Nezar Boreak, et al.
Published: (2021-08-01)

Adipose-Derived Stem Cells Secretome and Its Potential Application in “Stem Cell-Free Therapy”
by: Anna Trzyna, et al.
Published: (2021-06-01)

Mesenchymal stromal cell-derived exosome-rich fractionated secretome confers a hepatoprotective effect in liver injury
by: Apeksha Damania, et al.
Published: (2018-02-01)

Exofucosylation of Adipose Mesenchymal Stromal Cells Alters Their Secretome Profile
by: David García-Bernal, et al.
Published: (2020-11-01)

Mesenchymal Stem Cells Secretory Responses: Senescence Messaging Secretome and Immunomodulation Perspective
by: Victoria V. Lunyak, et al.
Published: (2017-12-01)

The value of in vitro cell culture of granulocytes in the detection of Ehrlichia Valor da cultura celular de granulócito in vitro na detecção de Ehrlichia
by: Alex Mutani, et al.
Published: (2001-01-01)

Effective healing of leprosy chronic plantar ulcers by application of human amniotic membrane stem cell secretome gel
by: F R Natallya, et al.
Published: (2019-01-01)

The Regenerative Role of the Fetal and Adult Stem Cell Secretome
by: Sveva Bollini, et al.
Published: (2013-12-01)

Translational Animal Models Provide Insight Into Mesenchymal Stromal Cell (MSC) Secretome Therapy
by: Rebecca M. Harman, et al.
Published: (2021-03-01)

Impact of mesenchymal stem cells’ secretome on glioblastoma pathophysiology
by: Joana Vieira de Castro, et al.
Published: (2017-10-01)

Granulocytes and Cells of Granulocyte Origin—The Relevant Players in Colorectal Cancer
by: Izabela Siemińska, et al.
Published: (2021-04-01)

Neural stem cell secretome and its role in the treatment of neurodegenerative disorders
by: Qian Zhang, Jia Li , Wenqiang An, Yiou Fan, Qilong Cao
Published: (2020-03-01)

Effect of Comedications and Endotoxins on Mesenchymal Stem Cell Secretomes, Migratory and Immunomodulatory Capacity
by: Nisha Durand, et al.
Published: (2019-04-01)

EXPRESSION OF T-bet FACTOR IN PERIPHERAL BLOOD MONONUCLEAR CELLS IN BRONCHIAL ASTHMA
by: V. N. Mineev, et al.
Published: (2014-07-01)

Cell-free therapy with the secretome of adipose tissue-derived stem cells in rats’ frozen-thawed ovarian grafts
by: Luciana Lamarão Damous, et al.
Published: (2018-11-01)

Preclinical Comparison of Stem Cells Secretome and Levodopa Application in a 6-Hydroxydopamine Rat Model of Parkinson’s Disease
by: Fábio G. Teixeira, et al.
Published: (2020-01-01)

Mesenchymal Stromal Cell-Based Bone Regeneration Therapies: From Cell Transplantation and Tissue Engineering to Therapeutic Secretomes and Extracellular Vesicles
by: Darja Marolt Presen, et al.
Published: (2019-11-01)

Veterinary Regenerative Medicine for Musculoskeletal Disorders: Can Mesenchymal Stem/Stromal Cells and Their Secretome Be the New Frontier?
by: Michela Mocchi, et al.
Published: (2020-06-01)

Proteomic Profiling of the Human Fetal Multipotent Mesenchymal Stromal Cells Secretome
by: Arseniy A. Lobov, et al.
Published: (2020-11-01)

Harnessing the Neural Stem Cell Secretome for Regenerative Neuroimmunology
by: Cory M. Willis, et al.
Published: (2020-11-01)

Proteomic Characterization of Human Neural Stem Cells and Their Secretome During in vitro Differentiation
by: Jakub Červenka, et al.
Published: (2021-01-01)

Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome
by: Frances D. Liu, et al.
Published: (2018-10-01)

Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome
by: Carl Randall Harrell, et al.
Published: (2019-05-01)

Revisiting the Advances in Isolation, Characterization and Secretome of Adipose-Derived Stromal/Stem Cells
by: Navneet Kumar Dubey, et al.
Published: (2018-07-01)

EVALUATION OF ADHERENCE FUNCTION FOR VARIOUS SUBPOPULATIONS OF PERIPHERAL BLOOD MONONUCLEARS TO ENDOTHELIAL CELLS
by: D. I. Sokolov, et al.
Published: (2014-07-01)