Computel: computation of mean telomere length from whole-genome next-generation sequencing data.

Telomeres are the ends of eukaryotic chromosomes, consisting of consecutive short repeats that protect chromosome ends from degradation. Telomeres shorten with each cell division, leading to replicative cell senescence. Deregulation of telomere length homeostasis is associated with the development o...

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Bibliographic Details
Main Authors: Lilit Nersisyan, Arsen Arakelyan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4414351?pdf=render