SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans.

SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans.

Central questions in regenerative biology include how stem cells are maintained and how they transition from self-renewal to differentiation. Germline stem cells (GSCs) in Caeno-rhabditis elegans provide a tractable in vivo model to address these questions. In this system, Notch signaling and PUF RN...

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Bibliographic Details
Main Authors:	Heaji Shin, Kimberly A Haupt, Aaron M Kershner, Peggy Kroll-Conner, Marvin Wickens, Judith Kimble
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-12-01
Series:	PLoS Genetics
Online Access:	http://europepmc.org/articles/PMC5741267?pdf=render

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