IL-18 Does not Increase Allergic Airway Disease in Mice When Produced by BCG

IL-18 Does not Increase Allergic Airway Disease in Mice When Produced by BCG

Whilst BCG inhibits allergic airway responses in murine models, IL-18 has adversary effects depending on its environment. We therefore constructed a BCG strain producing murine IL-18 (BCG-IL-18) and evaluated its efficiency to prevent an asthma-like reaction in mice. BALB/cByJ mice were sensitized (...

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Bibliographic Details
Main Authors: L. Amniai, F. Biet, P. Marquillies, C. Locht, J. Pestel, A.-B. Tonnel, C. Duez
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2007/67276

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