Original Research: Role of phosphodiesterases in modulation of BK channels in hypertensive pulmonary arterial smooth muscle

BK Ca channels regulate pulmonary arterial pressure, and protein kinase C (PKC) inhibits BK Ca channels, but little is known about PKC-mediated modulation of BK Ca channel activity in pulmonary arterial smooth muscle. Studies were carried out to determine mechanisms of PKC modulation of BK Ca channe...

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Bibliographic Details
Main Authors: Shu Zhu, Richard E. White, Scott A. Barman
Format: Article
Language:English
Published: SAGE Publishing 2008-06-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753465808091327