Solid Phase Chemical Synthesis and Structure - Activity Study of Brevinin - 2R and Analogues as Antimicrobial Peptides

Background: Brevinin-2R, as 25 amino acids peptide of the skin of Rana ridibunda frog, possesses potent antimicrobial and low hemolytic activity. It has an N-terminal hydrophilic region and a C-terminal loop that is delineated by an intra-disulfide bridge. In our study, Brevinin-2R and its diastere...

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Bibliographic Details
Main Authors: Hashem Yaghoubi, Alireza Asef, Amirhosein Banki
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-10-01
Series:Journal of Medical Bacteriology
Subjects:
Online Access:https://jmb.tums.ac.ir/index.php/jmb/article/view/39