Effect of okadaic acid on cultured clam heart cells: involvement of MAPkinase pathways

Effect of okadaic acid on cultured clam heart cells: involvement of MAPkinase pathways

Summary Okadaic acid (OA) is one of the main diarrhetic shellfish poisoning toxins and a potent inhibitor of protein phosphatases 1 and 2A. The downstream signal transduction pathways following the protein phosphatase inhibition are still unknown and the results of most of the previous studies are o...

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Bibliographic Details
Main Authors: Houda Hanana, Hélène Talarmin, Jean-Pierre Pennec, Mickael Droguet, Julie Morel, Germaine Dorange
Format: Article
Language:English
Published: The Company of Biologists 2012-09-01
Series:Biology Open
Subjects:
Clam
Heart
in vitro
Okadaic acid
MAPKinases
Apoptosis
Online Access:http://bio.biologists.org/content/1/12/1192

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