Long Telomeres Bypass the Requirement for Telomere Maintenance in Human Tumorigenesis
Despite the importance of telomere maintenance in cancer cell survival via the elongation of telomeres by telomerase reverse transcriptase (TERT) or alternative lengthening of telomeres (ALT), it had not been tested directly whether telomere maintenance is dispensable for human tumorigenesis. We en...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-02-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124711000143 |