Long Telomeres Bypass the Requirement for Telomere Maintenance in Human Tumorigenesis

Despite the importance of telomere maintenance in cancer cell survival via the elongation of telomeres by telomerase reverse transcriptase (TERT) or alternative lengthening of telomeres (ALT), it had not been tested directly whether telomere maintenance is dispensable for human tumorigenesis. We en...

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Bibliographic Details
Main Authors: Michael A.S. Taboski, David C.F. Sealey, Jennifer Dorrens, Chandrakant Tayade, Dean H. Betts, Lea Harrington
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124711000143