Bioactivity-guided isolation of alkamides from a cytotoxic fraction of the ethyl acetate extract of Anacyclus pyrethrum (L.) DC. roots.

Bioactivity-guided isolation of alkamides from a cytotoxic fraction of the ethyl acetate extract of Anacyclus pyrethrum (L.) DC. roots.

Introduction. The alcohol extract of Pellitory (Anacyclus pyrethrum) roots has been previously shown to exert anticancer activities on the Human Colorectal Cancer Cell Line (HCT) by targeting apoptosis, metastasis and cell cycle arrest. However, the nature of the cytotoxic molecules associated with...

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Bibliographic Details
Main Authors: Hamimed Souad, Boulebda Nadji, Laouer Hocine, Belkhiri Abdelmalik
Format: Article
Language:English
Published: Sciendo 2018-12-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
artemia salina
dl50
fractionation
alkamides
pellitory
Online Access:https://doi.org/10.1515/cipms-2018-0033
Description
Summary:Introduction. The alcohol extract of Pellitory (Anacyclus pyrethrum) roots has been previously shown to exert anticancer activities on the Human Colorectal Cancer Cell Line (HCT) by targeting apoptosis, metastasis and cell cycle arrest. However, the nature of the cytotoxic molecules associated with this activity remains unexplored.
ISSN:2084-980X
2300-6676

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