Inflammatory signature in acute-on-chronic liver failure includes increased expression of granulocyte genes ELANE, MPO and CD177

Abstract Acute-on-Chronic Liver Failure (ACLF) is associated with innate immune dysfunction and high short-term mortality. Neutrophils have been identified to influence prognosis in ACLF. Neutrophil biology is under-evaluated in ACLF. Therefore, we investigated neutrophil-specific genes and their as...

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Bibliographic Details
Main Authors: Rohini Saha, Sai Sanwid Pradhan, Shalimar, Prasenjit Das, Priyanka Mishra, Rohan Singh, Venketesh Sivaramakrishnan, Pragyan Acharya
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98086-6

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