Striatal Aβ peptide deposition mirrors dementia and differentiates DLB and PDD from other Parkinsonian syndromes

Striatal Aβ peptide deposition mirrors dementia and differentiates DLB and PDD from other Parkinsonian syndromes

Recent neuropathological studies have described widespread amyloid-β peptide (Aβ) deposition in the striatum of patients with Lewy body disorders, particularly in Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB). However, positron emission tomography (PET) studies usi...

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Bibliographic Details
Main Authors: M.E. Kalaitzakis, A.J. Walls, R.K.B. Pearce, S.M. Gentleman
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Dementia
Striatum
Amyloid-β peptide
[11C]PIB ligand
Dementia with Lewy bodies
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110003396

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