Expression and function of the insulin receptor substrate proteins in cancer

<p>Abstract</p> <p>The Insulin Receptor Substrate (IRS) proteins are cytoplasmic adaptor proteins that function as essential signaling intermediates downstream of activated cell surface receptors, many of which have been implicated in cancer. The IRS proteins do not contain any int...

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Bibliographic Details
Main Authors: Pankratz Shannon L, Mardilovich Katerina, Shaw Leslie M
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Cell Communication and Signaling
Online Access:http://www.biosignaling.com/content/7/1/14