TNF-α and temporal changes in sleep architecture in mice exposed to sleep fragmentation.

TNF-α and temporal changes in sleep architecture in mice exposed to sleep fragmentation.

TNF-α plays critical roles in host-defense, sleep-wake regulation, and the pathogenesis of various disorders. Increases in the concentration of circulating TNF-α after either sleep deprivation or sleep fragmentation (SF) appear to underlie excessive daytime sleepiness in patients with sleep apnea (O...

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Bibliographic Details
Main Authors: Navita Kaushal, Vijay Ramesh, David Gozal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3448632?pdf=render

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