The Anti-Inflammatory Effects of Dimethyl Fumarate in Astrocytes Involve Glutathione and Haem Oxygenase-1
DMF (dimethyl fumarate) exerts anti-inflammatory and prometabolic effects in a variety of cell types, and a formulation (BG-12) is being evaluated for monotherapy in multiple sclerosis patients. DMF modifies glutathione (GSH) levels that can induce expression of the anti-inflammatory protein HO-1 (h...
Main Authors: | Shao Xia Lin, Lucia Lisi, Cinzia Dello Russo, Paul E Polak, Anthony Sharp, Guy Weinberg, Sergey Kalinin, Douglas L Feinstein |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2011-03-01
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Series: | ASN Neuro |
Online Access: | https://doi.org/10.1042/AN20100033 |
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