Impact of Physical Obstacles on the Structural and Effective Connectivity of in silico Neuronal Circuits

Scaffolds and patterned substrates are among the most successful strategies to dictate the connectivity between neurons in culture. Here, we used numerical simulations to investigate the capacity of physical obstacles placed on a flat substrate to shape structural connectivity, and in turn collectiv...

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Bibliographic Details
Main Authors: Adriaan-Alexander Ludl, Jordi Soriano
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncom.2020.00077/full