(Patho-)Physiology of Na+/H+ Exchangers (NHEs) in the Digestive System

(Patho-)Physiology of Na+/H+ Exchangers (NHEs) in the Digestive System

Na+/H+ exchangers (NHEs) are expressed in virtually all human tissues and organs. Two major tasks of those NHE isoforms that are located in plasma membranes are cell volume control by Na+-uptake and cellular pH regulation by H+-extrusion. Several NHEs, particularly NHE 1–4 and 8, are involved in the...

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Bibliographic Details
Main Authors: Li Cao, Zhenglin Yuan, Mei Liu, Christian Stock
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Physiology
Subjects:
Na+/H+ exchangers
physiology
malfunction
pathophysiology
digestive system
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01566/full

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