Establishment and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Tigecycline in Critically Ill Patients
Utilizing tigecycline-d9 as an internal standard (IS), we establish and validate a simple, effective, and rapid liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantitative measurement of tigecycline (TGC) in patient plasma. Acetonitrile was used as a precipitant to process...
Main Authors: | Fen Yao, Yifan Wang, Yating Hou, Xipei Wang, Jinhua Lan, Zheng Wu, Yirong Wang, Chunbo Chen |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
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Series: | International Journal of Analytical Chemistry |
Online Access: | http://dx.doi.org/10.1155/2020/6671392 |
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