Efficiency of protein synthesis inhibition depends on tRNA and codon compositions.

Regulation and maintenance of protein synthesis are vital to all organisms and are thus key targets of attack and defense at the cellular level. Here, we mathematically analyze protein synthesis for its sensitivity to the inhibition of elongation factor EF-Tu and/or ribosomes in dependence of the sy...

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Bibliographic Details
Main Author: Sophia Rudorf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006979