Role Of Metalloproteinases in Plaque Rupture

Rupture of the fibrous cap over an atherosclerotic plaque is the main cause of myocardial infarctions and strokes. Plaques vulnerable to rupture have a relatively thin fibrous cap, are highly inflamed and contain less structural collagen. This suggests that increased production of proteases, includi...

Full description

Bibliographic Details
Main Author: Andrew C Newby
Format: Article
Language:English
Published: Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM) 2007-09-01
Series:International Journal of Gerontology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873959808700309