Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s Syndrome

Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s Syndrome

A 70-year-old man with systemic lupus erythematosus (SLE) presented with simultaneous right oculomotor nerve palsy and right facial nerve palsy. Brain magnetic resonance imaging and cerebrospinal fluid analysis revealed no abnormality. Coexistent Sjögren’s syndrome was diagnosed on the basis of anti...

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Main Authors: Natsuki Shima, Takamasa Murosaki, Shotaro Yamamoto, Akiko Miyanaga, Hiroi Kusaka, Katsuya Nagatani, Takao Nagashima, Mikio Sawada, Masahiro Iwamoto, Seiji Minota
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2019/4156781
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spelling doaj-60b1ec668eb947fa9249c79ec9ce2af62020-11-24T21:26:40ZengHindawi LimitedCase Reports in Rheumatology2090-68892090-68972019-01-01201910.1155/2019/41567814156781Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s SyndromeNatsuki Shima0Takamasa Murosaki1Shotaro Yamamoto2Akiko Miyanaga3Hiroi Kusaka4Katsuya Nagatani5Takao Nagashima6Mikio Sawada7Masahiro Iwamoto8Seiji Minota9Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanDivision of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanDivision of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanDivision of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanDivision of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanDivision of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanDivision of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanDepartment of Neurology, Haga Red Cross Hospital, Mooka, Tochigi, JapanDivision of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanDivision of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, JapanA 70-year-old man with systemic lupus erythematosus (SLE) presented with simultaneous right oculomotor nerve palsy and right facial nerve palsy. Brain magnetic resonance imaging and cerebrospinal fluid analysis revealed no abnormality. Coexistent Sjögren’s syndrome was diagnosed on the basis of anti-SS-A antibody positivity, salivary gland scintigraphy, and histological findings on minor salivary gland biopsy. As there was no obvious cause of multiple cranial neuropathies, we supposed that the palsies were induced by either of the underlying diseases. The patient was treated with a high-dose of prednisolone and intravenous cyclophosphamide, and both palsies recovered almost completely within two weeks.http://dx.doi.org/10.1155/2019/4156781
collection DOAJ
language English
format Article
sources DOAJ
author Natsuki Shima
Takamasa Murosaki
Shotaro Yamamoto
Akiko Miyanaga
Hiroi Kusaka
Katsuya Nagatani
Takao Nagashima
Mikio Sawada
Masahiro Iwamoto
Seiji Minota
spellingShingle Natsuki Shima
Takamasa Murosaki
Shotaro Yamamoto
Akiko Miyanaga
Hiroi Kusaka
Katsuya Nagatani
Takao Nagashima
Mikio Sawada
Masahiro Iwamoto
Seiji Minota
Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s Syndrome
Case Reports in Rheumatology
author_facet Natsuki Shima
Takamasa Murosaki
Shotaro Yamamoto
Akiko Miyanaga
Hiroi Kusaka
Katsuya Nagatani
Takao Nagashima
Mikio Sawada
Masahiro Iwamoto
Seiji Minota
author_sort Natsuki Shima
title Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s Syndrome
title_short Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s Syndrome
title_full Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s Syndrome
title_fullStr Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s Syndrome
title_full_unstemmed Simultaneous Oculomotor and Facial Nerve Palsies in a Patient with Systemic Lupus Erythematosus and Sjögren’s Syndrome
title_sort simultaneous oculomotor and facial nerve palsies in a patient with systemic lupus erythematosus and sjögren’s syndrome
publisher Hindawi Limited
series Case Reports in Rheumatology
issn 2090-6889
2090-6897
publishDate 2019-01-01
description A 70-year-old man with systemic lupus erythematosus (SLE) presented with simultaneous right oculomotor nerve palsy and right facial nerve palsy. Brain magnetic resonance imaging and cerebrospinal fluid analysis revealed no abnormality. Coexistent Sjögren’s syndrome was diagnosed on the basis of anti-SS-A antibody positivity, salivary gland scintigraphy, and histological findings on minor salivary gland biopsy. As there was no obvious cause of multiple cranial neuropathies, we supposed that the palsies were induced by either of the underlying diseases. The patient was treated with a high-dose of prednisolone and intravenous cyclophosphamide, and both palsies recovered almost completely within two weeks.
url http://dx.doi.org/10.1155/2019/4156781
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