Pre-treatment with Lactobacillus plantarum prevents severe pathogenesis in mice infected with Leptospira interrogans and may be associated with recruitment of myeloid cells.

Recent estimates on global morbidity and mortality caused by Leptospirosis point to one million cases and almost 60,000 deaths a year worldwide, especially in resource poor countries. We analyzed how a commensal probiotic immunomodulator, Lactobacillus plantarum, affects Leptospira interrogans patho...

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Bibliographic Details
Main Authors: Hari-Hara Potula, Luciana Richer, Catherine Werts, Maria Gomes-Solecki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5589268?pdf=render