Improvement in fatigue during Natalizumab treatment is linked to improvement in depression and day-time sleepiness

Improvement in fatigue during Natalizumab treatment is linked to improvement in depression and day-time sleepiness

Background: Fatigue is a frequent symptom in multiple sclerosis (MS) and often interrelated with depression and sleep disorders making symptomatic treatment decisions difficult. In the single-arm, observational phase IV TYNERGY study, relapsing-remitting MS patients showed a clinically meaningful de...

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Bibliographic Details
Main Authors: Iris-Katharina ePenner, Eva Catharina eSivertsdotter, Elisabeth G eCelius, Siegrid eFuchs, Karen eSchreiber, Sara eBerko, Anders eSvenningsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Neurology
Subjects:
Depression
Fatigue
multiple sclerosis (MS)
sleepiness
treatment response
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00018/full

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