Pituitary oncocytoma presenting as Cushing′s disease

Pituitary oncocytoma presenting as Cushing′s disease

A 19-year-old girl presented with classical features of Cushing′s syndrome. Endocrinal evaluation was consistent with pituitary source of ACTH; but imaging showed normal pituitary. Bilateral inferior petrosal sinus sampling confirmed the diagnosis. A successful remission was achieved after adenomect...

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Bibliographic Details
Main Authors: M K Garg, Reena Bharwaj, H C Pathak, Sandeep Kharb, Abhay Gundgurthi, Aditi Pandit, K S Brar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
Cushing′s syndrome
pituitary oncocytoma
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=4;spage=759;epage=762;aulast=Garg
Description
Summary:A 19-year-old girl presented with classical features of Cushing′s syndrome. Endocrinal evaluation was consistent with pituitary source of ACTH; but imaging showed normal pituitary. Bilateral inferior petrosal sinus sampling confirmed the diagnosis. A successful remission was achieved after adenomectomy by transphenoidal route. Histopathological examination was consistent with pituitary oncocytoma and immunohistochemistry was positive for synaptophysin, chromogranin, neuron specific enolase, S-100, ACTH, prolactin, and GH.
ISSN:2230-8210
2230-9500

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