Involvement of Transient Receptor Potential Cation Channel Member A1 activation in the irritation and pain response elicited by skin-lightening reagent hydroquinone

Abstract Hydroquinone (HQ) is one of the most frequently used and effective skin-lightening products to treat skin hyperpigmentation disorders, including postinflammatory hyperpigmentation, melasma and solar lentigines. HQ is also widely used in cosmetic products for skin whitening. However, HQ trea...

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Bibliographic Details
Main Authors: Yan Tai, Chuan Wang, Zhihua Wang, Yi Liang, Junying Du, Dongwei He, Xiaoyan Fan, Sven-Eric Jordt, Boyi Liu
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07651-5

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