In vitro cytotoxicity of the LDE: daunorubicin complex in acute myelogenous leukemia blast cells

In vitro cytotoxicity of the LDE: daunorubicin complex in acute myelogenous leukemia blast cells

Acute myelogenous leukemia (AML) blast cells show high-affinity degradation of low-density lipoprotein (LDL), suggesting an increased expression of cellular LDL receptors. LDE is a lipid microemulsion easily synthesized in vitro which is known to mimic the metabolic pathway of LDL. We used LDE as a...

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Bibliographic Details
Main Authors: P.E. Dorlhiac-Llacer, M.V. Marquezini, O. Toffoletto, R.C.G. Carneiro, R.C. Maranhão, D.A.F. Chamone
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
cytotoxicity
acute myelogenous leukemia
daunorubicin
low-density lipoprotein
LDE complex
RT-PCR
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000004

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