Tau monomer encodes strains

Tauopathies have diverse presentation, progression, and neuropathology. They are linked to tau prion strains, self-replicating assemblies of unique quaternary conformation, whose origin is unknown. Strains can be propagated indefinitely in cultured cells, and induce unique patterns of transmissible...

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Bibliographic Details
Main Authors: Apurwa M Sharma, Talitha L Thomas, DaNae R Woodard, Omar M Kashmer, Marc I Diamond
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-12-01
Series:eLife
Subjects:
Tau
Online Access:https://elifesciences.org/articles/37813