Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review
In oncology research, in vivo experiments on animal models have played and still play an essential role in understanding the etiology, evolution, diagnosis and therapy of human cancer. The purpose of this review is to highlight the importance of preclinical oncological studies on both experimental a...
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Romanian National Association of the Veterinary Products Manufacturers
2020-12-01
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| Series: | Medicamentul Veterinar |
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| Online Access: | http://www.veterinarypharmacon.com/docs/2258-2020_VD_14(2).ART.3.RO.pdf |
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doaj-607f0d993ba04840a677ef6f378aa0b42021-06-02T18:27:58ZengRomanian National Association of the Veterinary Products ManufacturersMedicamentul Veterinar1843-95272069-24632020-12-011426067Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review Diana Mihaela Alexandru0Ana-Maria Coman1Răzvan Dobre2Maria Crivineanu3Facultatea de Medicină Veterinară, Bucureşti Institutul Oncologic „Prof. Dr. Alexandru Trestioreanu", BucureştiFacultatea de Medicină Veterinară, BucureştiFaculty of Veterinary Medicine, BucharestIn oncology research, in vivo experiments on animal models have played and still play an essential role in understanding the etiology, evolution, diagnosis and therapy of human cancer. The purpose of this review is to highlight the importance of preclinical oncological studies on both experimental animals and pets that have developed spontaneous tumours, in the evolution of diagnostic methods and therapeutic management of neoplastic diseases. Also, a series of criteria underlying the elaboration of an in vivo study are emphasized, regarding the species, breed, sex, age of the animals, the selected tumour line and its purpose, taking into account the obligation to respect the ethical principles regarding the use of animals in research. http://www.veterinarypharmacon.com/docs/2258-2020_VD_14(2).ART.3.RO.pdfcanceroncological researchexperimental oncologyanimal models |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Diana Mihaela Alexandru Ana-Maria Coman Răzvan Dobre Maria Crivineanu |
| spellingShingle |
Diana Mihaela Alexandru Ana-Maria Coman Răzvan Dobre Maria Crivineanu Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review Medicamentul Veterinar cancer oncological research experimental oncology animal models |
| author_facet |
Diana Mihaela Alexandru Ana-Maria Coman Răzvan Dobre Maria Crivineanu |
| author_sort |
Diana Mihaela Alexandru |
| title |
Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_short |
Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_full |
Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_fullStr |
Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_full_unstemmed |
Importanţa modelelor animale în cercetarea oncologică: Un review / The importance of animal models in oncological research: A review |
| title_sort |
importanţa modelelor animale în cercetarea oncologică: un review / the importance of animal models in oncological research: a review |
| publisher |
Romanian National Association of the Veterinary Products Manufacturers |
| series |
Medicamentul Veterinar |
| issn |
1843-9527 2069-2463 |
| publishDate |
2020-12-01 |
| description |
In oncology research, in vivo experiments on animal models have played and still play an essential role in understanding the etiology, evolution, diagnosis and therapy of human cancer. The purpose of this review is to highlight the importance of preclinical oncological studies on both experimental animals and pets that have developed spontaneous tumours, in the evolution of diagnostic methods and therapeutic
management of neoplastic diseases. Also, a series of criteria underlying the elaboration of an in vivo study are emphasized, regarding the species, breed, sex, age of the animals, the selected tumour line and its purpose, taking into account the obligation to respect the ethical principles regarding the use of
animals in research. |
| topic |
cancer oncological research experimental oncology animal models |
| url |
http://www.veterinarypharmacon.com/docs/2258-2020_VD_14(2).ART.3.RO.pdf |
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