Negative correlation between brain glutathione level and negative symptoms in schizophrenia: a 3T 1H-MRS study.

Negative correlation between brain glutathione level and negative symptoms in schizophrenia: a 3T 1H-MRS study.

<h4>Background</h4>Glutathione (GSH), a major intracellular antioxidant, plays a role in NMDA receptor-mediated neurotransmission, which is involved in the pathophysiology of schizophrenia. In the present study, we aimed to investigate whether GSH levels are altered in the posterior medi...

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Main Authors: Daisuke Matsuzawa, Takayuki Obata, Yukihiko Shirayama, Hiroi Nonaka, Yoko Kanazawa, Eiji Yoshitome, Junichi Takanashi, Tsuyoshi Matsuda, Eiji Shimizu, Hiroo Ikehira, Masaomi Iyo, Kenji Hashimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18398470/pdf/?tool=EBI

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