Acquired Hemophilia presenting as Gross hematuria following Kidney Stone – A case report and review of the literature

• Main Authors: Max Schmidt-Bowman, Lael Reinstatler, Eric P. Raffin, Joseph E. Yared, John D. Seigne, Einar F. Sverrisson
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Urologia
• Series: International Brazilian Journal of Urology
• Subjects: Hematuria; Nephrolithiasis; Factor 8 deficiency, acquired [Supplementary Concept]
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382018000200390&lng=en&tlng=en
• ISSN: 1677-6119

ABSTRACT A rare condition in itself, acquired hemophilia A, seldom presents as isolated gross hematuria. It is a serious condition with a high mortality rate and thus clinical suspicion followed by prompt diagnosis is imperative (1). In fact, only 8 cases of such presentation of this condition have been reported thus far in the literature. Of these, none describe the initial presentation of hematuria with the inciting event of a kidney stone. We present a case of a 67-year-old man with signs and symptoms of nephrolithiasis accompanied by profuse hematuria, who was subsequently found to have developed expression of factor VIII inhibitor leading to acquired hemophilia A.