Cadmium and Copper Cross-Tolerance. Cu+ Alleviates Cd2 + Toxicity, and Both Cations Target Heme and Chlorophyll Biosynthesis Pathway in Rubrivivax gelatinosus

Cadmium and Copper Cross-Tolerance. Cu+ Alleviates Cd2 + Toxicity, and Both Cations Target Heme and Chlorophyll Biosynthesis Pathway in Rubrivivax gelatinosus

Cadmium, although not redox active is highly toxic. Yet, the underlying mechanisms driving toxicity are still to be characterized. In this study, we took advantage of the purple bacterium Rubrivivax gelatinosus strain with defective Cd2 +-efflux system to identify targets of this metal. Exposure of...

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Bibliographic Details
Main Authors: Anne Soisig Steunou, Anne Durand, Marie-Line Bourbon, Marion Babot, Reem Tambosi, Sylviane Liotenberg, Soufian Ouchane
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
CadA/ZntA
cadmium/copper
metal homeostasis
metal toxicity
cross-talk
[4Fe-4S]
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00893/full

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