Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs.

Prediction of RNA tertiary structure from sequence is an important problem, but generating accurate structure models for even short sequences remains difficult. Predictions of RNA tertiary structure tend to be least accurate in loop regions, where non-canonical pairs are important for determining th...

Full description

Bibliographic Details
Main Authors: Michael F Sloma, David H Mathews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5690697?pdf=render