Per3 expression in different tissues of Cebus apella

• Main Authors: Flávia Cal Sabino, José Américo de Oliveira, Mario Pedrazzoli
• Format: Article
• Language: English
• Published: Brazilian Association of Sleep and Latin American Federation of Sleep Societies 2016-10-01
• Series: Sleep Science
• Subjects: Circadian rhythms; Circadian expression; Per3 gene; Primate; Capuchin monkey
• Online Access: http://www.sciencedirect.com/science/article/pii/S1984006316300906

We present a study of Per3 expression in six different tissues of the non-human primate Cebus apella (capuchin monkey). The aim of this study was to verify whether the expression of the Per3 gene in different tissues of capuchin monkey occurs in a circadian pattern, its phase and the phase relationships between these different tissues during the 24 h of a day. We observed that gene expression oscillated in all of the tissues studied during this time period, although only the liver and muscle presented a robust circadian pattern. This preliminary study highlights the possibility of using Cebus apella as a model to study circadian rhythms at the gene expression level and opens an opportunity for future researches.