Influence of rimonabant treatment on peripheral blood mononuclear cells; flow cytometry analysis and gene expression profiling

Influence of rimonabant treatment on peripheral blood mononuclear cells; flow cytometry analysis and gene expression profiling

The cannabinoid receptor type 1 (CB1) antagonist rimonabant has been used as treatment for obesity. In addition, anti-proliferative effects on mitogen-activated leukocytes have been demonstrated in vitro. We have previously shown that rimonabant (SR141716A) induces cell death in ex vivo isolated mal...

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Bibliographic Details
Main Authors: Stefan Almestrand, Xiao Wang, Åsa Jeppsson-Ahlberg, Marcus Nordgren, Jenny Flygare, Birger Christensson, Stephan Rössner, Birgitta Sander
Format: Article
Language:English
Published: PeerJ Inc. 2015-06-01
Series:PeerJ
Subjects:
Blood leukocytes
Gene expression profiling
Cannabinoid receptor
Rimonabant
Flow cytometry
Online Access:https://peerj.com/articles/1056.pdf

Internet

https://peerj.com/articles/1056.pdf

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