Differential Vaginal Expression of Interleukin-1 System Cytokines in the Presence of Mycoplasma hominis and Ureaplasma urealyticum in Pregnant Women

Objective: The genital mycoplasmas, Ureaplasma urealyticum and Mycoplasma hominis, are commonly identified in the vagina of healthy pregnant women. However, these microorganisms are the most common isolates from the amniotic fluids of women in preterm labor. The mechanisms responsible for vaginal co...

Full description

Bibliographic Details
Main Authors: Kunihiko Doh, Parrin T. Barton, Irina Korneeva, Sriram C. Perni, Ann Marie Bongiovanni, Sara L. Tuttle, Daniel W. Skupski, Steven S. Witkin
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Infectious Diseases in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1080/10647440400003667
Description
Summary:Objective: The genital mycoplasmas, Ureaplasma urealyticum and Mycoplasma hominis, are commonly identified in the vagina of healthy pregnant women. However, these microorganisms are the most common isolates from the amniotic fluids of women in preterm labor. The mechanisms responsible for vaginal colonization and ascent to the uterus remain undetermined. We evaluated the association between U. urealyticum and M. hominis vaginal colonization and the presence of pro-inflammatory and anti-inflammatory interleukin-1 system components in asymptomatic pregnant women of different ethnicities.
ISSN:1064-7449
1098-0997