Lack of Desmin in Mice Causes Structural and Functional Disorders of Neuromuscular Junctions

Lack of Desmin in Mice Causes Structural and Functional Disorders of Neuromuscular Junctions

Desmin, the major intermediate filament (IF) protein in muscle cells, interlinks neighboring myofibrils and connects the whole myofibrillar apparatus to myonuclei, mitochondria, and the sarcolemma. However, desmin is also known to be enriched at postsynaptic membranes of neuromuscular junctions (NMJ...

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Bibliographic Details
Main Authors: Nane Eiber, Franziska Fröb, Mirjam Schowalter, Christian Thiel, Christoph S. Clemen, Rolf Schröder, Said Hashemolhosseini
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
desminopathy
skeletal muscle
neuromuscular junction
desmin
nicotinic acetylcholine receptor
postsynaptic gene
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2020.567084/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2020.567084/full

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