Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining

Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining

We report three cases of prostate adenocarcinoma appearing as bladder masses and misdiagnosed as muscle-invasive bladder cancer (MIBC). Patients were referred for consideration for radical cystectomy after initial pathological diagnosis suggested poorly differentiated bladder cancer. Pathological re...

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Main Authors: Van Schloegel, Syed M. Alam, Katie Dennis, Jeffrey Holzbeierlein, John A. Taylor III
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2020/8855451
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spelling doaj-6017c17267a94008a78704df01c272ba2020-12-28T01:30:47ZengHindawi LimitedCase Reports in Urology2090-69782020-01-01202010.1155/2020/8855451Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical StainingVan Schloegel0Syed M. Alam1Katie Dennis2Jeffrey Holzbeierlein3John A. Taylor III4Department of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyWe report three cases of prostate adenocarcinoma appearing as bladder masses and misdiagnosed as muscle-invasive bladder cancer (MIBC). Patients were referred for consideration for radical cystectomy after initial pathological diagnosis suggested poorly differentiated bladder cancer. Pathological review of tissue samples and subsequent immunohistochemical (IHC) staining confirmed advanced prostatic adenocarcinoma. Systemic therapy for prostate cancer was then initiated. These cases highlight the importance of patient history, physical exam, and IHC staining in consideration of a bladder mass, as these patients may have been subject to undue morbidity and surgical intervention without accurate pathologic diagnosis.http://dx.doi.org/10.1155/2020/8855451
collection DOAJ
language English
format Article
sources DOAJ
author Van Schloegel
Syed M. Alam
Katie Dennis
Jeffrey Holzbeierlein
John A. Taylor III
spellingShingle Van Schloegel
Syed M. Alam
Katie Dennis
Jeffrey Holzbeierlein
John A. Taylor III
Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
Case Reports in Urology
author_facet Van Schloegel
Syed M. Alam
Katie Dennis
Jeffrey Holzbeierlein
John A. Taylor III
author_sort Van Schloegel
title Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_short Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_full Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_fullStr Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_full_unstemmed Near-Miss Diagnoses of Solitary Bladder Tumors Highlight the Importance of Immunohistochemical Staining
title_sort near-miss diagnoses of solitary bladder tumors highlight the importance of immunohistochemical staining
publisher Hindawi Limited
series Case Reports in Urology
issn 2090-6978
publishDate 2020-01-01
description We report three cases of prostate adenocarcinoma appearing as bladder masses and misdiagnosed as muscle-invasive bladder cancer (MIBC). Patients were referred for consideration for radical cystectomy after initial pathological diagnosis suggested poorly differentiated bladder cancer. Pathological review of tissue samples and subsequent immunohistochemical (IHC) staining confirmed advanced prostatic adenocarcinoma. Systemic therapy for prostate cancer was then initiated. These cases highlight the importance of patient history, physical exam, and IHC staining in consideration of a bladder mass, as these patients may have been subject to undue morbidity and surgical intervention without accurate pathologic diagnosis.
url http://dx.doi.org/10.1155/2020/8855451
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AT syedmalam nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining
AT katiedennis nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining
AT jeffreyholzbeierlein nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining
AT johnatayloriii nearmissdiagnosesofsolitarybladdertumorshighlighttheimportanceofimmunohistochemicalstaining
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