Galanin transgenic mice with elevated circulating galanin levels alleviate demyelination in a cuprizone-induced MS mouse model.
Multiple Sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system (CNS) with a presumed autoimmune etiology. Approved treatments for MS are immunoregulatory and are able to reduce the inflammatory components of the disease. However, these treatments do not suppress progress...
Main Authors: | Lin Zhang, Wu Yu, Ingo Schroedter, Jiming Kong, Maria Vrontakis |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3307774?pdf=render |
Similar Items
-
The effect of galanin alone and combined with estrogen in a cuprizone-induced demyelination mouse model of multiple sclerosis
by: Zhang, Lin
Published: (2011) -
The effect of galanin alone and combined with estrogen in a cuprizone-induced demyelination mouse model of multiple sclerosis
by: Zhang, Lin
Published: (2011) -
Characterisation of the nociceptive phenotype of suppressible galanin overexpressing transgenic mice
by: Wynick David, et al.
Published: (2010-10-01) -
Molecular characterization of chicken galanin and galanin receptor family
by: Ho, Chi-wang, John., et al.
Published: (2013) -
Transgenic rescue of the galanin knockout nociceptive phenotype
by: Pope, Robert James Paul
Published: (2010)