RNA Replicons - A New Approach for Influenza Virus Immunoprophylaxis

RNA replicons are derived from either positive- or negative-strand RNA viruses. They represent disabled virus vectors that are not only avirulent, but also unable to revert to virulence. Due to autonomous RNA replication, RNA replicons are able to drive high level, cytosolic expression of recombinan...

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Bibliographic Details
Main Author: Gert Zimmer
Format: Article
Language:English
Published: MDPI AG 2010-01-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/2/2/413/