Fuyuan Decoction Enhances SOX9 and COL2A1 Expression and Smad2/3 Phosphorylation in IL-1β-Activated Chondrocytes

Fuyuan Decoction Enhances SOX9 and COL2A1 Expression and Smad2/3 Phosphorylation in IL-1β-Activated Chondrocytes

Fuyuan Decoction (FYD), a herbal formula in China, has been widely used for osteoarthritis (OA) treatment. Herein, we determined the effects of FYD on the expression of transcription factor SOX9 and its target gene collagen type II, alpha 1 (COL2A1) as well as the activation of Smad2/3 in interleuki...

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Bibliographic Details
Main Authors:	Yudi Zhang, Rongheng Li, Yu Zhong, Sihan Zhang, Lingyun Zhou, Shike Shang
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Evidence-Based Complementary and Alternative Medicine
Online Access:	http://dx.doi.org/10.1155/2015/821947

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