EFhd2 Affects Tau Liquid–Liquid Phase Separation

The transition of tau proteins from its soluble physiological conformation to the pathological aggregate forms found in Alzheimer’s disease and related dementias, is poorly understood. Therefore, understanding the process that modulates the formation of toxic tau oligomers and their conversion to pu...

Full description

Bibliographic Details
Main Authors: Irving E. Vega, Andrew Umstead, Nicholas M. Kanaan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Neuroscience
Subjects:
tau
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00845/full