Engineering regulatory networks for complex phenotypes in E. coli
Regulatory networks respond to environmental and genetic perturbations by reprogramming metabolism. Here the authors screen a library of 82 regulators with 110,120 mutations to map the regulatory network of 4000 genes.
Main Authors: | Rongming Liu, Liya Liang, Emily F. Freed, Alaksh Choudhury, Carrie A. Eckert, Ryan T. Gill |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-17721-4 |
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