The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging
Sites of infection and inflammation can be misleading in oncology PET/CT imaging because these areas commonly show 18F-FDG activity. Caution in the interpretation must be taken to avoid the misdiagnosis of malignancy. Utilization of both CT findings as well as patient history can help differentiate...
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Elsevier
2019-09-01
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| Series: | Biomedicine & Pharmacotherapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332219323376 |
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doaj-5ffad4c034934ed9bf2ad04f7b7804722021-05-20T07:38:42ZengElsevierBiomedicine & Pharmacotherapy0753-33222019-09-01117The impact of infection and inflammation in oncologic 18F-FDG PET/CT imagingW. Tania Rahman0Daniel J. Wale1Benjamin L. Viglianti2Danyelle M. Townsend3Matthew S. Manganaro4Milton D. Gross5Ka Kit Wong6Domenico Rubello7Nuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USANuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USA; Nuclear Medicine Service, Department of Veterans Affairs Health System, Ann Arbor, MI, USA; Corresponding author at: Nuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USA.Nuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USA; Nuclear Medicine Service, Department of Veterans Affairs Health System, Ann Arbor, MI, USADivision of Drug Discovery and Pharmaceutical Sciences, Medical University of South Carolina, USANuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USANuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USA; Nuclear Medicine Service, Department of Veterans Affairs Health System, Ann Arbor, MI, USANuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USADepartment of Nuclear Medicine, Radiology, Neuroradiology, Interventional Radiology, Pathology, Santa Maria della Misericordia Hospital, Rovigo, Italy; Corresponding author.Sites of infection and inflammation can be misleading in oncology PET/CT imaging because these areas commonly show 18F-FDG activity. Caution in the interpretation must be taken to avoid the misdiagnosis of malignancy. Utilization of both CT findings as well as patient history can help differentiate benign infectious and inflammatory processes from malignancy, although occasionally additional work-up may be required. This article discusses the mechanism of 18F-FDG uptake in infection and inflammation with illustrative examples.http://www.sciencedirect.com/science/article/pii/S075333221932337618F-FDG PET/CTInfectionInflammationImaging pitfalls |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
W. Tania Rahman Daniel J. Wale Benjamin L. Viglianti Danyelle M. Townsend Matthew S. Manganaro Milton D. Gross Ka Kit Wong Domenico Rubello |
| spellingShingle |
W. Tania Rahman Daniel J. Wale Benjamin L. Viglianti Danyelle M. Townsend Matthew S. Manganaro Milton D. Gross Ka Kit Wong Domenico Rubello The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging Biomedicine & Pharmacotherapy 18F-FDG PET/CT Infection Inflammation Imaging pitfalls |
| author_facet |
W. Tania Rahman Daniel J. Wale Benjamin L. Viglianti Danyelle M. Townsend Matthew S. Manganaro Milton D. Gross Ka Kit Wong Domenico Rubello |
| author_sort |
W. Tania Rahman |
| title |
The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging |
| title_short |
The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging |
| title_full |
The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging |
| title_fullStr |
The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging |
| title_full_unstemmed |
The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging |
| title_sort |
impact of infection and inflammation in oncologic 18f-fdg pet/ct imaging |
| publisher |
Elsevier |
| series |
Biomedicine & Pharmacotherapy |
| issn |
0753-3322 |
| publishDate |
2019-09-01 |
| description |
Sites of infection and inflammation can be misleading in oncology PET/CT imaging because these areas commonly show 18F-FDG activity. Caution in the interpretation must be taken to avoid the misdiagnosis of malignancy. Utilization of both CT findings as well as patient history can help differentiate benign infectious and inflammatory processes from malignancy, although occasionally additional work-up may be required. This article discusses the mechanism of 18F-FDG uptake in infection and inflammation with illustrative examples. |
| topic |
18F-FDG PET/CT Infection Inflammation Imaging pitfalls |
| url |
http://www.sciencedirect.com/science/article/pii/S0753332219323376 |
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