Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance.

Inheritance of phenotypic traits depends on two key events: replication of the determinant of that trait and partitioning of these copies between mother and daughter cells. Although these processes are well understood for nucleic acid-based genes, the mechanisms by which protein-only or prion-based...

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Bibliographic Details
Main Authors: Prasanna Satpute-Krishnan, Sara X Langseth, Tricia R Serio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1779812?pdf=render