Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance.
Inheritance of phenotypic traits depends on two key events: replication of the determinant of that trait and partitioning of these copies between mother and daughter cells. Although these processes are well understood for nucleic acid-based genes, the mechanisms by which protein-only or prion-based...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-02-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC1779812?pdf=render |