Anti-Cancer Potential of Synthetic Oleanolic Acid Derivatives and Their Conjugates with NSAIDs

Anti-Cancer Potential of Synthetic Oleanolic Acid Derivatives and Their Conjugates with NSAIDs

Naturally occurring pentacyclic triterpenoid oleanolic acid (OA) serves as a good scaffold for additional modifications to achieve synthetic derivatives. Therefore, a large number of triterpenoids have been synthetically modified in order to increase their bioactivity and their protective or therape...

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Bibliographic Details
Main Authors: Wanda Baer-Dubowska, Maria Narożna, Violetta Krajka-Kuźniak
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
oleanolic acid derivatives
Nrf2
NF-κB
NSAIDs
inflammation
oleanolic acid derivatives conjugates
Online Access:https://www.mdpi.com/1420-3049/26/16/4957

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