Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166
How and which cell surface molecules are taken up by clathrin-independent endocytosis is an ongoing area of research. Here, the authors show that the tumor marker CD166 is a clathrin-independent cargo that is taken up by endophilin-A3 and galectin-8, which regulates cancer cell migration.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2020-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-15303-y |
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doaj-5ff27bc5c991414daddf2ddab69036742021-05-11T09:13:31ZengNature Publishing GroupNature Communications2041-17232020-03-0111111310.1038/s41467-020-15303-yEndophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166Henri-François Renard0François Tyckaert1Cristina Lo Giudice2Thibault Hirsch3Cesar Augusto Valades-Cruz4Camille Lemaigre5Massiullah Shafaq-Zadah6Christian Wunder7Ruddy Wattiez8Ludger Johannes9Pierre van der Bruggen10David Alsteens11Pierre Morsomme12UCLouvain, Louvain Institute of Biomolecular Science and Technology, Group of Molecular PhysiologyUCLouvain, Louvain Institute of Biomolecular Science and Technology, Group of Molecular PhysiologyUCLouvain, Louvain Institute of Biomolecular Science and Technology, NanoBiophysics labUCLouvain, de Duve InstituteInstitut Curie, PSL Research University, Cellular and Chemical Biology unit, U1143 INSERM, UMR3666 CNRSUCLouvain, Louvain Institute of Biomolecular Science and Technology, Group of Molecular PhysiologyInstitut Curie, PSL Research University, Cellular and Chemical Biology unit, U1143 INSERM, UMR3666 CNRSInstitut Curie, PSL Research University, Cellular and Chemical Biology unit, U1143 INSERM, UMR3666 CNRSUMons, Research Institute for Biosciences, Proteomics and Microbiology LabInstitut Curie, PSL Research University, Cellular and Chemical Biology unit, U1143 INSERM, UMR3666 CNRSUCLouvain, de Duve InstituteUCLouvain, Louvain Institute of Biomolecular Science and Technology, NanoBiophysics labUCLouvain, Louvain Institute of Biomolecular Science and Technology, Group of Molecular PhysiologyHow and which cell surface molecules are taken up by clathrin-independent endocytosis is an ongoing area of research. Here, the authors show that the tumor marker CD166 is a clathrin-independent cargo that is taken up by endophilin-A3 and galectin-8, which regulates cancer cell migration.https://doi.org/10.1038/s41467-020-15303-y |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Henri-François Renard François Tyckaert Cristina Lo Giudice Thibault Hirsch Cesar Augusto Valades-Cruz Camille Lemaigre Massiullah Shafaq-Zadah Christian Wunder Ruddy Wattiez Ludger Johannes Pierre van der Bruggen David Alsteens Pierre Morsomme |
| spellingShingle |
Henri-François Renard François Tyckaert Cristina Lo Giudice Thibault Hirsch Cesar Augusto Valades-Cruz Camille Lemaigre Massiullah Shafaq-Zadah Christian Wunder Ruddy Wattiez Ludger Johannes Pierre van der Bruggen David Alsteens Pierre Morsomme Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166 Nature Communications |
| author_facet |
Henri-François Renard François Tyckaert Cristina Lo Giudice Thibault Hirsch Cesar Augusto Valades-Cruz Camille Lemaigre Massiullah Shafaq-Zadah Christian Wunder Ruddy Wattiez Ludger Johannes Pierre van der Bruggen David Alsteens Pierre Morsomme |
| author_sort |
Henri-François Renard |
| title |
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166 |
| title_short |
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166 |
| title_full |
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166 |
| title_fullStr |
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166 |
| title_full_unstemmed |
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166 |
| title_sort |
endophilin-a3 and galectin-8 control the clathrin-independent endocytosis of cd166 |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2020-03-01 |
| description |
How and which cell surface molecules are taken up by clathrin-independent endocytosis is an ongoing area of research. Here, the authors show that the tumor marker CD166 is a clathrin-independent cargo that is taken up by endophilin-A3 and galectin-8, which regulates cancer cell migration. |
| url |
https://doi.org/10.1038/s41467-020-15303-y |
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