Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics

Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics

In 2020, nearly one-third of new drugs on the global market were synthetic cannabinoids including the drug of abuse <i>N</i>-(1-adamantyl)-1-(5-pentyl)-1<i>H</i>-indazole-3-carboxamide (5F-APINACA, 5F-AKB48). Knowledge of 5F-APINACA metabolism provides a critical mechanistic...

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Bibliographic Details
Main Authors: Anna O. Pinson, Dakota L. Pouncey, Mary A. Schleiff, William E. Fantegrossi, Paul L. Prather, Anna Radominska-Pandya, Gunnar Boysen, Grover P. Miller
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
synthetic cannabinoid
5F-APINACA
5F-AKB48
P450
kinetics
drug abuse
Online Access:https://www.mdpi.com/1420-3049/25/20/4820

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