Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors

Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors

Abstract Background Reprogramming of cancers into normal-like tissues is an innovative strategy for cancer treatment. Recent reports demonstrate that defined factors can reprogram cancer cells into pluripotent stem cells. Glioblastoma multiforme (GBM) is the most common and aggressive malignant brai...

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Bibliographic Details
Main Authors: Jie Yuan, Fan Zhang, Dennis Hallahan, Zhen Zhang, Liming He, Ling-Gang Wu, Meng You, Qin Yang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
GBM
mTOR
Neuron
Protein kinase inhibitors
Reprogramming
ROCK
Online Access:http://link.springer.com/article/10.1186/s13046-018-0857-5

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