A Unique B-Family DNA Polymerase Facilitating Error-Prone DNA Damage Tolerance in Crenarchaeota

A Unique B-Family DNA Polymerase Facilitating Error-Prone DNA Damage Tolerance in Crenarchaeota

Sulfolobus islandicus codes for four DNA polymerases: three are of the B-family (Dpo1, Dpo2, and Dpo3), and one is of the Y-family (Dpo4). Western analysis revealed that among the four polymerases, only Dpo2 exhibited DNA damage-inducible expression. To investigate how these DNA polymerases could co...

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Bibliographic Details
Main Authors: Xu Feng, Xiaotong Liu, Ruyi Xu, Ruiliang Zhao, Wenqian Feng, Jianglan Liao, Wenyuan Han, Qunxin She
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
Subjects:
Sulfolobus islandicus
DNA polymerase
genetic analysis
DNA damage tolerance
Crenarchaeota
Dpo2
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01585/full

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