New 1,2,3-Triazole Scaffold Schiff Bases as Potential Anti-COVID-19: Design, Synthesis, DFT-Molecular Docking, and Cytotoxicity Aspects

New 1,2,3-Triazole Scaffold Schiff Bases as Potential Anti-COVID-19: Design, Synthesis, DFT-Molecular Docking, and Cytotoxicity Aspects

Schiff bases encompassing a 1,2,3-triazole motif were synthesized using an efficient multi-step synthesis. The formations of targeted Schiff base ligands were confirmed by different spectroscopic techniques (FT-IR, <sup>1</sup>H NMR, <sup>13</sup>C NMR, and CHN analysis). The...

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Bibliographic Details
Main Authors: Musa A. Said, Daoud J. O. Khan, Fawzia F. Al-blewi, Nadia S. Al-Kaff, Adeeb A. Ali, Nadjet Rezki, Mohamed Reda Aouad, Mohamed Hagar
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
1,2,3-triazole
Schiff base (SB)
DFT-QSAR
COVID-19
molecular docking
cytotoxicity
Online Access:https://www.mdpi.com/2076-393X/9/9/1012

Internet

https://www.mdpi.com/2076-393X/9/9/1012

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